Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683401 | 0.92 | CHRM4 (0.51) | MCHR1LMNAMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL4683393 | 0.89 | FGFR1 (0.48) | MCHR1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4687404 | 0.87 | MCHR1 (0.47) | MCHR1LMNAMAPTSMN1; SMN2MCHR2 | |
| SCHEMBL4236614 | 0.87 | MAPT (0.52) | MCHR1LMNAMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL4683166 | 0.87 | HRH3 (0.48) | MAPTKMT2AMEN1 | |
| SCHEMBL4687069 | 0.87 | HRH3 (0.48) | MAPTKMT2AMEN1 | |
| SCHEMBL4688728 | 0.85 | MCHR1 (0.47) | MCHR1MAPTSMN1; SMN2MCHR2KMT2A | |
| SCHEMBL4683459 | 0.85 | MAPT (0.45) | MCHR1MAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4683722 | 0.84 | MAPT (0.49) | MCHR1LMNAMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL4689248 | 0.84 | MCHR1 (0.45) | MCHR1LMNAMAPTSMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |