Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.48 |
| ▸ | SLC5A7 | Q9GZV3 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683166 | 1.00 | HRH3 (0.48) | HRH3SLC5A7CYP2D6KDRMEN1 | |
| SCHEMBL4688677 | 0.97 | HRH3 (0.48) | HRH3SLC5A7CYP2D6 | |
| SCHEMBL4682983 | 0.91 | HRH3 (0.56) | HRH3MAPT | |
| SCHEMBL4784378 | 0.90 | SLC5A7 (0.45) | SLC5A7CYP2D6 | |
| SCHEMBL4683393 | 0.89 | FGFR1 (0.48) | KDRMEN1GAAMAPTHTT | |
| SCHEMBL4683735 | 0.88 | QPCT (0.43) | HRH3SLC5A7MEN1GAAMAPT | |
| SCHEMBL4683459 | 0.88 | MAPT (0.45) | KDRMEN1GAAMAPTHTT | |
| SCHEMBL4687209 | 0.87 | HRH3 (0.41) | HRH3NAMPT | |
| SCHEMBL4233292 | 0.87 | HRH3 (0.48) | HRH3SLC5A7 | |
| SCHEMBL4236845 | 0.87 | HRH3 (0.48) | HRH3SLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |