SCHEMBL468352

SCHEMBL468352

C[C@H](NC(=O)Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.60
MAPT P10636 4/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
POLB P06746 2/20 0.60
APAF1 O14727 1/20 0.60
RECQL P46063 1/20 0.60
ALDH1A1 P00352 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
HPGD P15428 1/20 0.57
ACE P12821 2/20 0.56
ECE1 P42892 1/20 0.55
SLC6A2 P23975 1/20 0.55
FNTA P49354 1/20 0.55
FNTB P49356 1/20 0.55
LMNA P02545 2/20 0.54
ALOX15 P16050 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6081797 1.00 KDM4E (0.60) KDM4EMAPTL3MBTL1POLBAPAF1
SCHEMBL29394133 1.00 KDM4E (0.60) KDM4EMAPTL3MBTL1POLBAPAF1
SCHEMBL13038297 0.90 ALDH1A1 (0.57) KDM4EMAPTL3MBTL1POLBAPAF1
SCHEMBL12562523 0.90 ALDH1A1 (0.57) KDM4EMAPTL3MBTL1POLBAPAF1
SCHEMBL13074806 0.89 ALDH1A1 (0.56) KDM4EMAPTL3MBTL1POLBAPAF1
SCHEMBL10593441 0.87 ALDH1A1 (0.71) KDM4EMAPTL3MBTL1POLBAPAF1
SCHEMBL29881777 0.87 KDM4E (0.58) KDM4EMAPTL3MBTL1POLBAPAF1
SCHEMBL26616624 0.87 MAPT (0.67) KDM4EMAPTL3MBTL1POLBAPAF1
SCHEMBL30692740 0.87 KDM4E (0.58) KDM4EMAPTL3MBTL1POLBAPAF1
SCHEMBL26616376 0.87 MAPT (0.67) KDM4EMAPTL3MBTL1POLBAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11751573-B2 Seaweed composition PORT LOUIS BERNARD (SC) 2023-09-12 US claimed
CN-114828648-A Pet food compositions 希尔氏宠物营养品公司 2022-07-29 CN claimed
EP-4017281-A1 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2022-06-29 EP claimed
WO-2021127701-A1 PET FOOD COMPOSITIONS HILL'S PET NUTRITION, INC. (US) 2021-06-24 WO claimed
US-20200337315-A1 SEAWEED COMPOSITION PORT LOUIS BERNARD (SC) 2020-10-29 US claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
WO-2016181414-A1 PROCESS FOR THE SYNTHESIS OF IVACAFTOR AND RELATED COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-11-17 WO claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20150045496-A1 THERMO-REVERSIBLE POLYBUTADIENE RUBBER BLEND WITH SELF-HEALING NATURE RELIANCE INDUSTRIES LIMITED (IN) 2015-02-12 US claimed
EP-1047391-A1 ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 2000-11-02 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
WO-1999030679-A1 α-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 1999-06-24 WO claimed
US-5657064-A Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1997-08-12 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673782-A2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1995-09-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS KDM4E 2134/4885MAPT 2153/4885L3MBTL1 1390/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS KDM4E 2134/4885MAPT 2153/4885L3MBTL1 1390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.