Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.60 |
| ▸ | FPR2 | P25090 | 5/20 | 0.55 |
| ▸ | FPR1 | P21462 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680177 | 0.82 | F10 (0.80) | F10FPR2FPR1 | |
| SCHEMBL4680188 | 0.78 | F10 (0.69) | F10FPR2FPR1 | |
| SCHEMBL4681012 | 0.76 | F10 (1.00) | F10FPR2FPR1 | |
| SCHEMBL4680132 | 0.75 | F10 (0.61) | F10FPR2FPR1 | |
| SCHEMBL4682683 | 0.75 | F10 (0.69) | F10FPR2FPR1 | |
| SCHEMBL4683366 | 0.75 | F10 (0.69) | F10FPR2FPR1 | |
| SCHEMBL4680775 | 0.74 | FPR2 (0.72) | F10FPR2FPR1 | |
| SCHEMBL4680369 | 0.74 | F10 (0.77) | F10FPR2FPR1 | |
| SCHEMBL20555885 | 0.74 | FPR2 (0.77) | F10FPR2FPR1 | |
| SCHEMBL18955218 | 0.74 | FPR2 (0.77) | F10FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337251-B1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2008-08-20 | — | — | EP | claimed |
| EP-1337251-B1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2008-08-20 | — | — | EP | disclosed |