⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71305 | 0.78 | — | — | |
| SCHEMBL5034136 | 0.78 | ALDH1A1 (0.41) | — | |
| SCHEMBL10997419 | 0.74 | CES1 (0.59) | — | |
| SCHEMBL120572 | 0.73 | — | — | |
| SCHEMBL28838211 | 0.73 | — | — | |
| SCHEMBL2460267 | 0.73 | — | — | |
| SCHEMBL7146267 | 0.73 | — | — | |
| SCHEMBL11445342 | 0.72 | CES1 (0.61) | — | |
| SCHEMBL27958808 | 0.72 | — | — | |
| SCHEMBL29058422 | 0.71 | CES1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113501819-B | Pyridoimidazole substituted quinazolinone derivative, and synthetic method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2024-02-02 | — | — | CN | claimed |
| CN-116239594-A | 6- (imidazo [1,2-a ] pyridin-6-yl) quinazoline derivatives and uses thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-09 | — | — | CN | claimed |
| CN-114890932-A | First total synthesis process of indole alkaloid Luteoride A | 大理大学 | 2022-08-12 | — | — | CN | claimed |
| US-20220089542-A1 | PROCESS FOR PREPARATION OF ALDEHYDE SCAVENGER AND INTERMEDIATES | ALDEYRA THERAPEUTICS, INC. | 2022-03-24 | — | — | US | claimed |
| CN-113501819-A | Pyridoimidazole-substituted quinazolinone derivative and synthesis method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2021-10-15 | — | — | CN | claimed |
| WO-2020223717-A1 | PROCESS FOR PREPARATION OF ALDEHYDE SCAVENGER AND INTERMEDIATES | ALDEYRA THERAPEUTICS, INC. (US) | 2020-11-05 | — | — | WO | claimed |
| WO-2009018368-A1 | COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2009-02-05 | — | — | WO | claimed |
| EP-0021923-B1 | PROCESS FOR THE PREPARATION OF VINCAMINE DERIVATIVES | SYNTHELABO (FR) | 1983-09-07 | — | — | EP | claimed |
| US-4316029-A | Synthesis of vincaminic acid derivatives | SYNTHELABO (FR) | 1982-02-16 | — | — | US | claimed |
| EP-4219501-B1 | COMPOUND CONTAINING 2,4-THIAZOLE RING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | UNIV SHANDONG (CN) | 2026-01-28 | — | — | EP | disclosed |
| US-20260008781-A1 | NEW BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM | HOFFMANN LA ROCHE (US) | 2026-01-08 | — | — | US | disclosed |
| US-20250388584-A1 | TPK AGONIST AND METHOD FOR TREATING NEURODEGENERATIVE DISEASES USING SAME | SHANGHAI RAISING PHARMACEUTICAL CO LTD (CN) | 2025-12-25 | — | — | US | disclosed |
| EP-4408848-B1 | BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 POSITIVE ALLOSTERIC MODULATORS | HOFFMANN LA ROCHE (CH) | 2025-11-05 | — | — | EP | disclosed |
| US-12365687-B2 | Benzodiazepine derivatives as GABA A gamma 1 PAM | HOFFMANN-LA ROCHE INC. (US) | 2025-07-22 | — | — | US | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0209237-A2 | Vinyl-glycyl-amino-beta-lactam derivatives | BEECHAM GROUP PLC (GB) | 1987-01-21 | — | — | EP | disclosed |
| US-4560690-A | ANTISECRETORY AGENTS, HISTAMINE H2-ANTAGONISTS | PFIZER INC. (US) | 1985-12-24 | — | — | US | disclosed |
| US-4316029-A | Synthesis of vincaminic acid derivatives | SYNTHELABO (FR) | 1982-02-16 | — | — | US | disclosed |
| US-4316029-A | Synthesis of vincaminic acid derivatives | SYNTHELABO (FR) | 1982-02-16 | — | — | US | disclosed |