Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.44 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682878 | 0.95 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1BSPTLC2ABCB11 | |
| SCHEMBL4684483 | 0.86 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BSPTLC2ABCB11 | |
| SCHEMBL4687810 | 0.82 | AVPR2 (0.48) | AVPR2AVPR1AAVPR1BSPTLC2ABCB11 | |
| SCHEMBL4682873 | 0.81 | AVPR2 (0.45) | AVPR2AVPR1AAVPR1BSPTLC2ABCB11 | |
| SCHEMBL4682142 | 0.80 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1BSPTLC2ABCB11 | |
| SCHEMBL7241452 | 0.80 | AVPR2 (0.51) | AVPR2AVPR1AAVPR1BABCB11ADRB2 | |
| SCHEMBL7349412 | 0.79 | SPTLC2 (0.51) | AVPR2AVPR1AAVPR1BSPTLC2ABCB11 | |
| SCHEMBL7352456 | 0.78 | AVPR2 (0.56) | AVPR2AVPR1AAVPR1BABCB11ADRB2 | |
| SCHEMBL4683086 | 0.78 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BSPTLC2ABCB11 | |
| SCHEMBL4684494 | 0.77 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BSPTLC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |