Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.64 |
| ▸ | HRH2 | P25021 | 12/20 | 0.60 |
| ▸ | HRH1 | P35367 | 12/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622889 | 0.96 | HRH3 (0.65) | HRH3HRH2HRH1MEN1 | |
| Oxalic Acid SCHEMBL4505073 | 0.93 | HRH3 (0.57) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL4684886 | 0.90 | HRH3 (0.66) | HRH3HRH2HRH1MEN1 | |
| Oxalic Acid SCHEMBL4491231 | 0.90 | HRH3 (0.61) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL4494406 | 0.88 | HRH3 (0.68) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL14150224 | 0.85 | HRH3 (0.68) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL4491586 | 0.85 | HRH3 (0.68) | HRH3HRH2HRH1MEN1 | |
| Oxalic Acid SCHEMBL4493442 | 0.83 | HRH3 (0.60) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL1978291 | 0.83 | HRH3 (0.71) | HRH3HRH2HRH1 | |
| Oxalic Acid SCHEMBL4495484 | 0.81 | HRH3 (0.61) | HRH3HRH2HRH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720544-B1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2008-03-19 | — | — | EP | disclosed |