Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 17/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686281 | 0.93 | PTGER1 (0.74) | PTGER1CYP1A2 | |
| SCHEMBL4683994 | 0.89 | PTGER1 (0.58) | PTGER1CYP1A2 | |
| SCHEMBL4683995 | 0.88 | PTGER1 (0.77) | PTGER1CYP1A2 | |
| SCHEMBL4686703 | 0.88 | PTGER1 (0.77) | PTGER1 | |
| SCHEMBL4686738 | 0.88 | PTGER1 (0.64) | PTGER1MAPK14CYP1A2 | |
| SCHEMBL4685311 | 0.87 | PTGER1 (0.85) | PTGER1CYP1A2 | |
| SCHEMBL4683400 | 0.86 | PTGER1 (0.59) | PTGER1CYP1A2 | |
| SCHEMBL4684108 | 0.84 | PTGER1 (0.56) | PTGER1CYP1A2 | |
| SCHEMBL4683974 | 0.84 | PTGER1 (0.65) | PTGER1 | |
| SCHEMBL4683336 | 0.83 | PTGER1 (0.59) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675832-B1 | HETEROCYCLYL COMPOUNDS | GLAXO GROUP LTD (GB) | 2008-02-20 | — | — | EP | claimed |