SCHEMBL4686703

SCHEMBL4686703

Cc1cc(OC(=O)O)nn1Cc1cc(Cl)ccc1OCc1ccc(F)cc1F

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4686281 0.93 PTGER1 (0.74) PTGER1
SCHEMBL4686789 0.91 PTGER1 (0.64) PTGER1
SCHEMBL4685288 0.91 PTGER1 (0.77) PTGER1
SCHEMBL4683995 0.89 PTGER1 (0.77) PTGER1
SCHEMBL4680878 0.89 PTGER1 (0.65) PTGER1
SCHEMBL4686738 0.89 PTGER1 (0.64) PTGER1
SCHEMBL4685366 0.88 PTGER1 (0.65) PTGER1
SCHEMBL4683882 0.88 PTGER1 (0.61) PTGER1
SCHEMBL4684660 0.88 PTGER1 (0.74) PTGER1
SCHEMBL4085124 0.87 PTGER1 (1.00) PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675832-B1 HETEROCYCLYL COMPOUNDS GLAXO GROUP LTD (GB) 2008-02-20 EP claimed