Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | GHSR | Q92847 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17189471 | 0.93 | EPHX1 (0.72) | EPHX1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL468415 | 0.93 | EPHX1 (0.72) | EPHX1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL15358666 | 0.93 | EPHX1 (0.72) | EPHX1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL822126 | 0.93 | EPHX1 (0.72) | EPHX1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL17189466 | 0.93 | EPHX1 (0.72) | EPHX1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL10599703 | 0.90 | MAPT (0.67) | EPHX1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL21766543 | 0.85 | EPHX1 (0.62) | EPHX1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL11034317 | 0.85 | EPHX1 (0.84) | EPHX1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL11033138 | 0.85 | EPHX1 (0.84) | EPHX1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL6438783 | 0.85 | EPHX1 (0.84) | EPHX1ALDH1A1HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |