Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | CLPP | Q16740 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683024 | 0.92 | NAMPT (0.39) | NAMPTTNIKKCNH2HRH3DRD4 | |
| SCHEMBL4684887 | 0.80 | MAOB (0.42) | NAMPTMAOBDRD3KCNH2KMT2A | |
| SCHEMBL4687652 | 0.78 | MAOB (0.39) | NAMPTMAOBDRD3KCNH2HTT | |
| SCHEMBL4322879 | 0.76 | DRD4 (0.42) | MAOBDRD3KCNH2HRH3DRD4 | |
| SCHEMBL4322869 | 0.75 | MAOB (0.44) | NAMPTMAOBDRD3KCNH2KMT2A | |
| SCHEMBL4337990 | 0.74 | MAOB (0.41) | NAMPTMAOBDRD3KCNH2KMT2A | |
| SCHEMBL4321955 | 0.74 | DRD3 (0.43) | NAMPTMAPTMAOBDRD3KCNH2 | |
| SCHEMBL4320344 | 0.73 | CCR2 (0.44) | NAMPTMAPTMAOBDRD3KCNH2 | |
| SCHEMBL4320847 | 0.73 | MAOB (0.41) | NAMPTMAOBDRD3KCNH2KMT2A | |
| SCHEMBL4332720 | 0.73 | CCR2 (0.43) | MAOBDRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973906-A1 | HYDROXYDIHYDROPYRIDOPY RAZINE-1,8-DIONES AND METHODS FOR INHIBITING HIV INTEGRASE | Virochem Pharma Inc. (CA) | 2008-10-01 | — | — | EP | claimed |
| WO-2006066414-A1 | HYDROXYDIHYDROPYRIDOPY RAZINE-1,8-DIONES AND METHODS FOR INHIBITING HIV INTEGRASE | VIROCHEM PHARMA INC. (CA) | 2006-06-29 | — | — | WO | claimed |