Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688585 | 0.93 | CCR3 (0.47) | CCR3EPHX2NAMPTKMT2AMAPT | |
| SCHEMBL4683401 | 0.91 | CHRM4 (0.51) | CCR3FLT3KITKMT2AMAPT | |
| SCHEMBL4688015 | 0.90 | HRH3 (0.48) | — | |
| SCHEMBL4687959 | 0.90 | HRH3 (0.48) | — | |
| SCHEMBL4687209 | 0.89 | HRH3 (0.41) | CCR3EPHX2NAMPTEPHX1 | |
| SCHEMBL4684667 | 0.89 | TOP2A (0.44) | EPHX2NAMPTKMT2AHDAC1HDAC2 | |
| SCHEMBL4686982 | 0.87 | CCR3 (0.49) | CCR3KMT2AMAPTMCHR1TP53 | |
| SCHEMBL4683722 | 0.86 | MAPT (0.49) | CCR3KMT2AMAPTMCHR1TP53 | |
| SCHEMBL4686596 | 0.86 | CCR3 (0.57) | CCR3KMT2AMAPTMCHR1OPRM1 | |
| SCHEMBL4683553 | 0.86 | CCR3 (0.49) | CCR3EPHX2KMT2AMAPTMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |