Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.49 |
| ▸ | PNLIP | P16233 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | UBE2M | P61081 | 2/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686982 | 0.92 | CCR3 (0.49) | CCR3MAPTCCR2OPRM1OPRD1 | |
| SCHEMBL4683722 | 0.91 | MAPT (0.49) | CCR3MAPTOPRM1OPRD1LMNA | |
| SCHEMBL4686596 | 0.91 | CCR3 (0.57) | CCR3MAPTCCR2OPRM1OPRD1 | |
| SCHEMBL4686797 | 0.91 | CCR3 (0.50) | CCR3PNLIPEPHX2CCR2OPRM1 | |
| SCHEMBL4688476 | 0.90 | CCR3 (0.51) | CCR3MAPTCCR2OPRM1OPRD1 | |
| SCHEMBL4688687 | 0.89 | CCR3 (0.48) | CCR3MAPTCCR2OPRM1OPRD1 | |
| SCHEMBL4689248 | 0.89 | MCHR1 (0.45) | CCR3MAPTLMNAUSP2HTT | |
| SCHEMBL4688148 | 0.89 | CCR3 (0.49) | CCR3EPHX2MAPTCCR2OPRM1 | |
| SCHEMBL4237817 | 0.89 | PNLIP (0.42) | PNLIPMAPTSTSMCHR1HRH3 | |
| SCHEMBL4683393 | 0.86 | FGFR1 (0.48) | CCR3MAPTOPRM1OPRD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |