Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688912 | 0.90 | QPCT (0.39) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL4687360 | 0.90 | CCR3 (0.43) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL4687180 | 0.88 | CCR3 (0.41) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL4235345 | 0.87 | PKM (0.38) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL4683459 | 0.87 | MAPT (0.45) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL4683109 | 0.86 | CCR3 (0.43) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL4688218 | 0.85 | CCR3 (0.43) | MEN1MAPTHTTKMT2AQPCT | |
| SCHEMBL4683361 | 0.83 | CCR3 (0.43) | QPCTKDRMCHR1 | |
| SCHEMBL4687031 | 0.82 | NAMPT (0.44) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL4233925 | 0.81 | PKM (0.39) | MEN1GAAMAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |