Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.46 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688001 | 0.90 | CCR3 (0.40) | MCHR1MCHR2HTR3ACCR3KDR | |
| SCHEMBL4236573 | 0.89 | MCHR1 (0.45) | MCHR1MCHR2SMN1; SMN2NPSR1KDR | |
| SCHEMBL4688079 | 0.89 | MAPT (0.42) | MCHR1MAPTKMT2ATP53ALDH1A1 | |
| SCHEMBL4688728 | 0.86 | MCHR1 (0.47) | MCHR1MCHR2SMN1; SMN2NPSR1HTR3A | |
| SCHEMBL4686821 | 0.85 | CHRM4 (0.48) | MCHR1MCHR2SMN1; SMN2CCR3MAPT | |
| SCHEMBL4687404 | 0.85 | MCHR1 (0.47) | MCHR1MCHR2SMN1; SMN2NPSR1CCR3 | |
| SCHEMBL4240513 | 0.84 | MCHR1 (0.40) | MCHR1SMN1; SMN2NPSR1MAPTMEN1 | |
| SCHEMBL4683061 | 0.84 | MCHR1 (0.45) | MCHR1MCHR2SMN1; SMN2NPSR1HTR3A | |
| SCHEMBL4683393 | 0.84 | FGFR1 (0.48) | MCHR1MCHR2SMN1; SMN2NPSR1HTR3A | |
| SCHEMBL4689248 | 0.83 | MCHR1 (0.45) | MCHR1MCHR2SMN1; SMN2NPSR1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |