Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686821 | 0.92 | CHRM4 (0.48) | MAPTMCHR1ALDH1A1KMT2ARAB9A | |
| SCHEMBL4686765 | 0.89 | MCHR1 (0.46) | MAPTMCHR1ALDH1A1KMT2ARAB9A | |
| SCHEMBL4228379 | 0.87 | MCHR1 (0.41) | MAPTTSHRMCHR1ALDH1A1POLB | |
| SCHEMBL4240513 | 0.85 | MCHR1 (0.40) | MAPTTSHRMCHR1ALDH1A1KMT2A | |
| SCHEMBL4686962 | 0.85 | CACNA1B (0.51) | MAPTTSHRMCHR1ALDH1A1POLB | |
| SCHEMBL4744081 | 0.84 | MCHR1 (0.38) | MAPTMCHR1ALDH1A1POLBKMT2A | |
| SCHEMBL4683722 | 0.83 | MAPT (0.49) | MAPTTSHRMCHR1ALDH1A1KMT2A | |
| SCHEMBL4683524 | 0.81 | MCHR1 (0.41) | MAPTTSHRMCHR1ALDH1A1KMT2A | |
| SCHEMBL4683022 | 0.81 | MCHR1 (0.40) | MAPTTSHRMCHR1ALDH1A1KMT2A | |
| SCHEMBL4687113 | 0.80 | KMT2A (0.43) | MAPTMCHR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |