Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 4/20 | 0.40 |
| ▸ | HAT1 | O14929 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686248 | 0.78 | CNR1 (0.50) | NPC1RAB9AHPGDCNR1CNR2 | |
| SCHEMBL3140995 | 0.75 | ACACB (0.48) | NPC1RAB9ACNR1CNR2 | |
| SCHEMBL14227540 | 0.74 | CNR2 (0.52) | NPC1RAB9ACNR1PPARACNR2 | |
| SCHEMBL12664470 | 0.73 | NPC1 (0.55) | NPC1RAB9ATDP1TAAR1CNR1 | |
| SCHEMBL12519205 | 0.72 | NPC1 (0.46) | NPC1RAB9AEP300HAT1TDP1 | |
| SCHEMBL24192360 | 0.69 | NPC1 (0.54) | NPC1RAB9AHPGDTDP1TAAR1 | |
| SCHEMBL19281410 | 0.69 | NPC1 (0.54) | NPC1RAB9AHPGDTDP1TAAR1 | |
| SCHEMBL24192005 | 0.69 | NPC1 (0.54) | NPC1RAB9AHPGDTDP1TAAR1 | |
| SCHEMBL3144439 | 0.69 | ALDH1A1 (0.40) | NPC1RAB9ATDP1 | |
| SCHEMBL4072352 | 0.68 | HPGD (0.49) | NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768954-A4 | 2-METHYLPROPANAMIDES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-05-28 | — | — | EP | claimed |
| EP-1768954-A2 | 2-METHYLPROPANAMIDES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-04-04 | — | — | EP | claimed |
| WO-2006002361-A2 | 2-METHYLPROPANAMIDES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-01-05 | — | — | WO | claimed |