1,6-Hexanediol

1,6-Hexanediol

SCHEMBL468690

CC(C)(C)OOC(=O)OC(C)(C)C.OCCCCCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
HDAC6 Q9UBN7 2/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
CYP4F2 P78329 4/20 0.38
CYP4A11 Q02928 4/20 0.38
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ELANE P08246 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1333110 0.85 TSHR (0.40) TDP1HDAC6HDAC1HDAC2ALDH1A1
SCHEMBL2230627 0.81 TDP1 (0.47) TDP1HDAC6HDAC1HDAC2CYP4F2
SCHEMBL8506489 0.78 CYP4F2 (0.44) TDP1CYP4F2CYP4A11ALDH1A1TSHR
SCHEMBL9749295 0.78 TDP1 (0.43) TDP1CYP4F2CYP4A11ALDH1A1TSHR
1,6-Hexanediol SCHEMBL9747029 0.78 TDP1 (0.43) TDP1CYP4F2CYP4A11ALDH1A1TSHR
1,6-Hexanediol SCHEMBL11422342 0.75 TSHR (0.50) TDP1CYP4F2CYP4A11ALDH1A1TSHR
SCHEMBL3800212 0.74 TSHR (0.36) TDP1HDAC6HDAC1HDAC2ALDH1A1
SCHEMBL9601113 0.73 TDP1 (0.47) TDP1HDAC6HDAC1HDAC2CYP4F2
SCHEMBL3920190 0.73 TSHR (0.39) TDP1ALDH1A1TSHRHSD17B10
SCHEMBL303730 0.72 TSHR (0.44) TDP1ALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228708-A9 MILLABLE FLUOROSILICONE RUBBER COMPOSITION HAVING HEAT RESISTANCE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-11 US disclosed
CN-115943186-B Silicone composition and thermally conductive silicone cured product having high thermal conductivity 信越化学工业株式会社 2024-05-07 CN disclosed
US-20240132672-A1 MILLABLE FLUOROSILICONE RUBBER COMPOSITION HAVING HEAT RESISTANCE SHINETSU CHEMICAL CO (JP) 2024-04-25 US disclosed
EP-3533838-B1 HEAT-RESISTANT MILLABLE SILICONE RUBBER COMPOSITION SHINETSU CHEMICAL CO (JP) 2024-02-21 EP disclosed
US-20240006723-A1 SILICONE LAMINATE AND BATTERY FUJI POLYMER INDUSTRIES CO., LTD. (JP) 2024-01-04 US disclosed
US-20230407011-A1 MILLABLE-TYPE SILICONE RUBBER COMPOSITION AND SILICONE RUBBER CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-21 US disclosed
EP-4253465-A1 MILLABLE-TYPE SILICONE RUBBER COMPOSITION AND SILICONE RUBBER CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-04 EP disclosed
CN-116669951-A Silicone rubber molded body and method for producing same 富士高分子工业株式会社 2023-08-29 CN disclosed
EP-4230406-A1 SILICONE MULTILAYER BODY Fuji Polymer Industries Co., Ltd. (JP) 2023-08-23 EP disclosed
CN-116529930-A Silicone laminate 富士高分子工业株式会社 2023-08-01 CN disclosed
US-10954385-B2 Heat-resistant millable silicone rubber composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-03-23 US disclosed
CN-111480207-A Conductive paste 住友电木株式会社 2020-07-31 CN disclosed
CN-110615992-A Chopped fiber reinforced organic silicon resin composition and preparation method thereof 中国工程物理研究院化工材料研究所 2019-12-27 CN disclosed
US-20190330457-A1 POLYOLEFIN RUBBER COMPOSITION Amaderus Holdings Co., Ltd. (JP) 2019-10-31 US disclosed
EP-3533838-A1 HEAT-RESISTANT MILLABLE SILICONE RUBBER COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2019-09-04 EP disclosed
US-10106668-B2 Silicone rubber composition for making key pad and key pad SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-10-23 US disclosed
US-20170349726-A1 SILICONE RUBBER COMPOSITION FOR MAKING KEY PAD AND KEY PAD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-07 US disclosed
EP-2388286-A2 Silicone rubber composition Shin-Etsu Chemical Co., Ltd. (JP) 2011-11-23 EP disclosed
JP-2005206660-A CROSS-LINKING AGENT COMPOSITION AND THERMALLY CURING SILICONE RUBBER COMPOSITION USING THE SAME SHIN ETSU CHEM CO LTD 2005-08-04 JP disclosed
US-5138005-A Suspension polymerization; aqueous medium; controlled agitation NIPPON ZEON CO., LTD. (JP) 1992-08-11 US disclosed