Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786969 | 0.87 | EPHX2 (0.52) | HDAC1HDAC2EPHX2EPHX1ALDH1A1 | |
| SCHEMBL4683604 | 0.87 | MAPT (0.52) | HDAC1HDAC2EPHX2EPHX1ALDH1A1 | |
| SCHEMBL4689241 | 0.86 | HDAC1 (0.64) | HDAC1HDAC2EPHX2EPHX1ALDH1A1 | |
| SCHEMBL4685424 | 0.86 | HDAC1 (0.51) | HDAC1HDAC2EPHX2EPHX1ALDH1A1 | |
| SCHEMBL4787348 | 0.85 | EPHX2 (0.55) | HDAC1HDAC2EPHX2EPHX1ALDH1A1 | |
| SCHEMBL4682919 | 0.84 | HDAC1 (0.51) | HDAC1HDAC2EPHX2EPHX1ALDH1A1 | |
| SCHEMBL4687419 | 0.84 | MEN1 (0.56) | HDAC1HDAC2EPHX2EPHX1ALDH1A1 | |
| SCHEMBL4686066 | 0.82 | HDAC1 (0.49) | HDAC1HDAC2EPHX2EPHX1ALDH1A1 | |
| SCHEMBL4787051 | 0.81 | TBXA2R (0.62) | MGLLMEN1GAAKMT2ATBXA2R | |
| SCHEMBL4235398 | 0.81 | PKM (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |