Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A7 | Q9GZV3 | 8/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688677 | 0.93 | HRH3 (0.48) | SLC5A7CYP2D6RAB9AQPCT | |
| SCHEMBL4683166 | 0.90 | HRH3 (0.48) | SLC5A7CYP2D6 | |
| SCHEMBL4687069 | 0.90 | HRH3 (0.48) | SLC5A7CYP2D6 | |
| SCHEMBL4232714 | 0.88 | SLC5A7 (0.45) | SLC5A7CYP2D6MCHR1 | |
| SCHEMBL4684561 | 0.87 | SLC5A7 (0.44) | SLC5A7PDE4ARAB9ANPC1 | |
| SCHEMBL4683735 | 0.84 | QPCT (0.43) | SLC5A7PDE4ARAB9ANPC1MCHR1 | |
| SCHEMBL4682983 | 0.83 | HRH3 (0.56) | CCR3 | |
| SCHEMBL4687209 | 0.80 | HRH3 (0.41) | RAB9ACCR3QPCT | |
| SCHEMBL4234320 | 0.80 | HRH3 (0.48) | SLC5A7CYP2D6RAB9ANPC1 | |
| SCHEMBL4688728 | 0.79 | MCHR1 (0.47) | SLC5A7CYP2D6RAB9AMCHR1MCHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |