Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798847 | 0.74 | EPHX2 (0.36) | L3MBTL1EPHX2ALDH1A1GAA | |
| SCHEMBL27420857 | 0.71 | EPHX2 (0.34) | L3MBTL1EPHX2ALDH1A1MAPK1HRH3 | |
| SCHEMBL9936383 | 0.69 | L3MBTL1 (0.35) | L3MBTL1EPHX2KDM4EGAA | |
| SCHEMBL827936 | 0.66 | SMN1; SMN2 (0.61) | EPHX2ALDH1A1EPHX1KDM4E | |
| SCHEMBL5021846 | 0.66 | USP2 (0.44) | L3MBTL1ALDH1A1EPHX1KDM4E | |
| SCHEMBL18010859 | 0.64 | NPSR1 (0.62) | EPHX2ALDH1A1EPHX1KDM4E | |
| SCHEMBL931220 | 0.64 | NPSR1 (0.62) | EPHX2ALDH1A1EPHX1KDM4E | |
| SCHEMBL931108 | 0.64 | NPSR1 (0.62) | EPHX2ALDH1A1EPHX1KDM4E | |
| SCHEMBL19669665 | 0.64 | NPSR1 (0.62) | EPHX2ALDH1A1EPHX1KDM4E | |
| SCHEMBL15713113 | 0.64 | NPSR1 (0.62) | EPHX2ALDH1A1EPHX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |