Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687283 | 0.77 | AVPR2 (0.51) | AVPR2AVPR1AMAPT | |
| SCHEMBL8635109 | 0.76 | AVPR2 (0.44) | AVPR2AVPR1AHTR1A | |
| SCHEMBL8627652 | 0.74 | AVPR2 (0.43) | AVPR2AVPR1ALMNA | |
| SCHEMBL8632578 | 0.73 | AVPR2 (0.44) | AVPR2AVPR1ALMNA | |
| SCHEMBL8827651 | 0.72 | AVPR2 (0.44) | AVPR2HDAC1HDAC6HTR1A | |
| SCHEMBL8627648 | 0.72 | AVPR2 (0.47) | AVPR2AVPR1ALMNAHTR1A | |
| SCHEMBL8827641 | 0.71 | AVPR2 (0.40) | AVPR2AVPR1AHDAC1HDAC6HTR1A | |
| SCHEMBL8632575 | 0.70 | AVPR2 (0.46) | AVPR2AVPR1ALMNAHTR1A | |
| SCHEMBL4687327 | 0.70 | AVPR2 (0.55) | AVPR2AVPR1AMAPT | |
| SCHEMBL7348955 | 0.69 | AVPR2 (0.55) | AVPR2AVPR1ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |