Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827638 | 0.79 | AVPR2 (0.43) | AVPR2HDAC1HDAC6IDO1KCNH2 | |
| SCHEMBL8827651 | 0.76 | AVPR2 (0.44) | AVPR2LTA4HHDAC1HDAC6IDO1 | |
| SCHEMBL4687283 | 0.74 | AVPR2 (0.51) | AVPR2AVPR1APOLB | |
| SCHEMBL4687300 | 0.71 | AVPR2 (0.43) | AVPR2HDAC1HDAC6HTR1AAVPR1A | |
| SCHEMBL9088002 | 0.69 | AVPR2 (0.44) | AVPR2HDAC1HDAC6ALDH1A1HTR1A | |
| SCHEMBL8827575 | 0.66 | AVPR2 (0.47) | AVPR2HDAC1HDAC6ALDH1A1AVPR1A | |
| SCHEMBL8827639 | 0.66 | AVPR2 (0.65) | AVPR2HDAC1HDAC6IDO1KCNH2 | |
| Hydrochloric Acid SCHEMBL8827701 | 0.66 | F10 (0.51) | AVPR2HDAC1HDAC6IDO1KCNH2 | |
| SCHEMBL8827569 | 0.66 | AVPR2 (0.49) | AVPR2HDAC1HDAC6IDO1KCNH2 | |
| SCHEMBL8827697 | 0.66 | AVPR2 (0.50) | AVPR2HDAC1HDAC6IDO1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677299-A | VASOPRESSIN OR OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-10-14 | — | — | US | disclosed |