Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236335 | 0.89 | PKM (0.53) | PKMTAS1R3TAS1R1CYP2C9CYP2C19 | |
| SCHEMBL4234125 | 0.87 | PKM (0.56) | PKMTAS1R3TAS1R1CYP2C9CYP2C19 | |
| SCHEMBL4242559 | 0.86 | PKM (0.49) | PKMTAS1R3TAS1R1MAPK1MEN1 | |
| SCHEMBL4683708 | 0.86 | PKM (0.63) | PKMTAS1R3TAS1R1CYP2C9CYP2C19 | |
| SCHEMBL5149842 | 0.86 | PKM (0.63) | PKMTAS1R3TAS1R1CYP2C9CYP2C19 | |
| SCHEMBL4236717 | 0.85 | PKM (0.54) | PKMTAS1R3TAS1R1CYP2C9CYP2C19 | |
| SCHEMBL4685639 | 0.83 | MAPT (0.40) | MAPK1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL4238927 | 0.82 | PKM (0.54) | PKMTAS1R3TAS1R1CYP2C9CYP2C19 | |
| SCHEMBL4687749 | 0.81 | EPHX1 (0.49) | PKMALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL4242160 | 0.81 | PKM (0.46) | PKMTAS1R3TAS1R1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |