Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 6/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468783 | 1.00 | NOD1 (0.50) | NOD1PLA2G2CTLR2SIRT6SIRT1 | |
| SCHEMBL7043917 | 0.99 | NOD1 (0.52) | NOD1PLA2G2CTLR2SIRT6SIRT1 | |
| SCHEMBL468769 | 0.99 | NOD1 (0.52) | NOD1PLA2G2CTLR2SIRT6SIRT1 | |
| SCHEMBL7043919 | 0.99 | NOD1 (0.52) | NOD1PLA2G2CTLR2SIRT6SIRT1 | |
| SCHEMBL468829 | 0.99 | NOD1 (0.52) | NOD1PLA2G2CTLR2SIRT6SIRT1 | |
| SCHEMBL8773297 | 0.99 | NOD1 (0.52) | NOD1PLA2G2CTLR2SIRT6SIRT1 | |
| SCHEMBL468770 | 0.99 | NOD1 (0.52) | NOD1PLA2G2CTLR2SIRT6SIRT1 | |
| SCHEMBL468828 | 0.99 | NOD1 (0.52) | NOD1PLA2G2CTLR2SIRT6SIRT1 | |
| SCHEMBL468919 | 0.95 | NOD1 (0.45) | NOD1PLA2G2CTLR2SIRT6SIRT1 | |
| SCHEMBL468917 | 0.95 | NOD1 (0.45) | NOD1PLA2G2CTLR2SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42902-E1 | N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use | TRISTRATA, INC. (US) | 2011-11-08 | — | — | US | claimed |