Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233405 | 0.97 | NPC1 (0.44) | PKMRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL4236654 | 0.96 | PKM (0.47) | PKMRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL4228647 | 0.95 | PKM (0.43) | PKMRAB9ANPC1SMN1; SMN2NAMPT | |
| SCHEMBL13699433 | 0.87 | PKM (0.47) | PKMRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL4234174 | 0.87 | PKM (0.43) | PKMTAS1R3TAS1R1TOP2A | |
| SCHEMBL4229212 | 0.86 | MCHR1 (0.51) | PKMRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL4235406 | 0.85 | HRH3 (0.46) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL4232733 | 0.85 | PKM (0.45) | PKMRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL13699303 | 0.85 | PKM (0.45) | PKMRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL13699330 | 0.85 | PKM (0.45) | PKMRAB9ANPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |