Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051700 | 0.96 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1ALOX5APFFAR1AKR1B1 | |
| SCHEMBL4059423 | 0.94 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1ALOX5APFFAR1AKR1B1 | |
| SCHEMBL4049859 | 0.90 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1ALOX5APFFAR1AKR1B1 | |
| SCHEMBL4052136 | 0.88 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5APFFAR1AKR1B1 | |
| SCHEMBL4059466 | 0.84 | PDE4A (0.33) | ALOX5APFFAR4 | |
| SCHEMBL4052958 | 0.81 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1ALOX5APFFAR1AKR1B1 | |
| SCHEMBL14159715 | 0.81 | ALOX5AP (0.34) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4055033 | 0.81 | ALOX5AP (0.35) | CYSLTR2CYSLTR1ALOX5APFFAR1AKR1B1 | |
| SCHEMBL5331476 | 0.80 | TBXA2R (0.42) | — | |
| SCHEMBL5335837 | 0.80 | CYSLTR1 (0.39) | CYSLTR2CYSLTR1ALOX5APFFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| EP-1560834-B1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL LAB (ES) | 2008-06-25 | — | — | EP | disclosed |
| EP-1560834-A1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | Almirall Prodesfarma, S.A. (ES) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004043966-A1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-05-27 | — | — | WO | disclosed |