Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.60 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.56 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.56 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL27999204 | 1.00 | GABRR1 (0.63) | GABRR1LMNAEGLN1ALKBH5SUCNR1 | |
| Glutarate SCHEMBL722388 | 0.88 | SLC22A6 (0.65) | GABRR1LMNAEGLN1ALKBH5SUCNR1 | |
| Glutarate SCHEMBL28412854 | 0.88 | SLC22A6 (0.65) | GABRR1LMNAEGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL367246 | 0.86 | OR51E2 (0.77) | GABRR1LMNAEGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL6597777 | 0.86 | OR51E2 (0.77) | GABRR1LMNAEGLN1ALKBH5SUCNR1 | |
| Glycine SCHEMBL528230 | 0.86 | OR51E2 (0.77) | GABRR1LMNAEGLN1ALKBH5SUCNR1 | |
| Glycine SCHEMBL8152756 | 0.86 | OR51E2 (0.77) | GABRR1LMNAEGLN1ALKBH5SUCNR1 | |
| Butyric Acid SCHEMBL27662187 | 0.83 | HDAC3 (0.68) | GABRR1LMNAOR51E2GLRA1SLC6A9 | |
| Glycine SCHEMBL6937710 | 0.83 | GLRA1 (0.71) | GABRR1LMNAEGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL30870384 | 0.83 | LMNA (0.64) | GABRR1LMNAEGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3506762-A1 | IMPROVED PRE-EMERGENT HERBICIDE | W. Neudorff GmbH KG (DE) | 2019-07-10 | — | — | EP | claimed |
| WO-2018041916-A1 | IMPROVED PRE-EMERGENT HERBICIDE | W. NEUDORFF GMBH KG (DE) | 2018-03-08 | — | — | WO | claimed |
| EP-2579722-B1 | SELECTIVE HERBICIDES WITH ACTIVATOR ADJUVANTS | NEUDORFF W GMBH KG (DE) | 2016-11-23 | — | — | EP | claimed |
| US-8568759-B2 | Pesticidal compositions and methods | W. NEUDORFF GMBH KG (DE) | 2013-10-29 | — | — | US | claimed |
| EP-2579722-A1 | SELECTIVE HERBICIDES WITH ACTIVATOR ADJUVANTS | W. Neudorff GmbH KG (DE) | 2013-04-17 | — | — | EP | claimed |
| US-20110306495-A1 | SELECTIVE HERBICIDES WITH ACTIVATOR ADJUVANTS | W. NEUDORFF GMBH KG | 2011-12-15 | — | — | US | claimed |
| US-20110081425-A1 | PESTICIDAL COMPOSITIONS AND METHODS | W. NEUDORFF GMBH KG (DE) | 2011-04-07 | — | — | US | claimed |
| EP-1489909-A1 | TRANSITION METAL CHELATES AS SELECTIVE HERBICIDE | W. NEUDORFF GmbH KG (DE) | 2004-12-29 | — | — | EP | claimed |
| US-20030181332-A1 | Composition and method for selective herbicide | W. NEUDORFF GMBH KG | 2003-09-25 | — | — | US | claimed |
| WO-2003073856-A1 | TRANSITION METAL CHELATES AS SELECTIVE HERBICIDE | W. NEUDORFF GMBH KG (DE) | 2003-09-12 | — | — | WO | claimed |
| US-20230354814-A1 | ENHANCED HERBICIDAL COMPOSITIONS OF TRANSITION METAL CHELATES | W NEUDORFF GMBH KG (DE) | 2023-11-09 | — | — | US | disclosed |
| EP-3999227-A1 | METAL-ORGANIC FRAMEWORKS HAVING LOCALIZED DEFECTS FOR GAS SEPARATIONS | ExxonMobil Research and Engineering Company (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-114096592-A | Metal organic framework with localized defects for gas separation | 埃克森美孚研究工程公司 | 2022-02-25 | — | — | CN | disclosed |
| WO-2021011111-A1 | METAL-ORGANIC FRAMEWORKS HAVING LOCALIZED DEFECTS FOR GAS SEPARATIONS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2021-01-21 | — | — | WO | disclosed |
| EP-3506762-A1 | IMPROVED PRE-EMERGENT HERBICIDE | W. Neudorff GmbH KG (DE) | 2019-07-10 | — | — | EP | disclosed |
| EP-1489909-A1 | TRANSITION METAL CHELATES AS SELECTIVE HERBICIDE | W. NEUDORFF GmbH KG (DE) | 2004-12-29 | — | — | EP | disclosed |
| US-20040062785-A1 | Mixture of chelate compound and carrier; killing pests upon digestion | W. NEUDORFF GMBH KG (DE) | 2004-04-01 | — | — | US | disclosed |
| EP-1402776-A1 | Pesticidal compositions and methods | W. Neudorff GmbH KG (DE) | 2004-03-31 | — | — | EP | disclosed |
| US-20030181332-A1 | Composition and method for selective herbicide | W. NEUDORFF GMBH KG | 2003-09-25 | — | — | US | disclosed |
| WO-2003073856-A1 | TRANSITION METAL CHELATES AS SELECTIVE HERBICIDE | W. NEUDORFF GMBH KG (DE) | 2003-09-12 | — | — | WO | disclosed |