Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690417 | 0.88 | OPRM1 (0.51) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL4690415 | 0.86 | OPRM1 (0.49) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL4688809 | 0.82 | OPRM1 (0.56) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL4690361 | 0.82 | OPRM1 (0.56) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL27564282 | 0.82 | OPRM1 (0.59) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL4688145 | 0.81 | OPRM1 (0.54) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL1846545 | 0.81 | OPRM1 (0.55) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL4687336 | 0.81 | OPRM1 (0.58) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL1846845 | 0.81 | OPRM1 (0.55) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL4689989 | 0.80 | OPRM1 (0.55) | OPRM1OPRD1OPRK1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443046-B1 | NOVEL 4-(2FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | KYORIN SEIYAKU KK (JP) | 2008-12-17 | — | — | EP | claimed |