Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628661 | 0.85 | ATM (0.52) | ATMALDH1A1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL945435 | 0.76 | ATM (0.44) | ATMALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL8484583 | 0.76 | KMT2A (0.42) | ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL8483277 | 0.76 | KMT2A (0.45) | ATMALDH1A1TP53L3MBTL1MEN1 | |
| SCHEMBL8481052 | 0.74 | KMT2A (0.43) | ATMALDH1A1TP53L3MBTL1MEN1 | |
| SCHEMBL8486542 | 0.74 | KMT2A (0.38) | ATMALDH1A1TP53MEN1KMT2A | |
| SCHEMBL2644261 | 0.74 | KMT2A (0.33) | L3MBTL1KMT2A | |
| SCHEMBL31487813 | 0.74 | TP53 (0.62) | ATMALDH1A1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL7217209 | 0.72 | TP53 (0.71) | ATMALDH1A1SMN1; SMN2TP53MEN1 | |
| SCHEMBL3632776 | 0.71 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |