Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693041 | 0.91 | F10 (0.44) | F10 | |
| SCHEMBL4744688 | 0.88 | F10 (0.46) | F10 | |
| SCHEMBL5432757 | 0.86 | F10 (0.47) | F10F2F11 | |
| SCHEMBL4747707 | 0.85 | F10 (0.49) | F10F2F11 | |
| SCHEMBL5429153 | 0.84 | F10 (0.47) | F10F2 | |
| SCHEMBL4686838 | 0.84 | F10 (0.48) | F10F2 | |
| SCHEMBL4688557 | 0.83 | F10 (0.47) | F10F2 | |
| SCHEMBL4784793 | 0.83 | F10 (0.48) | F10F2 | |
| SCHEMBL4687187 | 0.82 | F10 (0.50) | F10F2 | |
| SCHEMBL4690862 | 0.81 | F10 (0.44) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603572-A4 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1603572-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |