SCHEMBL4693041

SCHEMBL4693041

COCC(C)(C)C(=O)N1CC[CH]C(NC(=O)c2ccc(-n3ccccc3=O)cc2)C1C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4688619 0.91 F10 (0.42) F10
SCHEMBL4744688 0.89 F10 (0.46) F10
SCHEMBL4854738 0.84 F10 (0.44) F10
SCHEMBL5432757 0.84 F10 (0.47) F10
SCHEMBL4747707 0.83 F10 (0.49) F10
SCHEMBL5429153 0.82 F10 (0.47) F10
SCHEMBL4686838 0.82 F10 (0.48) F10
SCHEMBL4687839 0.81 F10 (0.46) F10
SCHEMBL4688557 0.81 F10 (0.47) F10
SCHEMBL4784793 0.81 F10 (0.48) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603572-A4 LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2008-06-25 EP disclosed
EP-1603572-A1 LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS Bristol-Myers Squibb Company (US) 2005-12-14 EP disclosed
WO-2004082687-A1 LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-09-30 WO disclosed