Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 20/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167998 | 0.90 | LTA4H (0.51) | LTA4HKCNH2EPHX2 | |
| SCHEMBL29674639 | 0.90 | LTA4H (0.51) | LTA4HKCNH2EPHX2 | |
| SCHEMBL2168678 | 0.85 | LTA4H (0.57) | LTA4HKCNH2EPHX2 | |
| SCHEMBL2167904 | 0.81 | LTA4H (0.56) | LTA4HKCNH2EPHX2 | |
| SCHEMBL2170463 | 0.80 | LTA4H (0.54) | LTA4HKCNH2EPHX2 | |
| SCHEMBL2169597 | 0.79 | LTA4H (0.55) | LTA4HKCNH2EPHX2 | |
| SCHEMBL2168385 | 0.79 | LTA4H (0.58) | LTA4HKCNH2EPHX2 | |
| SCHEMBL2168642 | 0.78 | LTA4H (0.49) | LTA4HKCNH2EPHX2 | |
| SCHEMBL4693779 | 0.78 | LTA4H (0.54) | LTA4HKCNH2EPHX2 | |
| SCHEMBL4693774 | 0.77 | LTA4H (0.59) | LTA4HKCNH2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660492-B1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-20 | — | — | EP | claimed |