SCHEMBL468872

SCHEMBL468872

CC(=O)NCC(=O)N(CC(=O)O)C(=O)CN

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 2/20 0.32
ADRA1A P35348 1/20 0.32
GLRA1 P23415 1/20 0.31
SLC6A9 P48067 1/20 0.31
OR51E2 Q9H255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633350 0.84 GLRA1 (0.32) GLRA1SLC6A9OR51E2
SCHEMBL98566 0.80 GLRA1 (0.47) ADRA1AGLRA1SLC6A9OR51E2
SCHEMBL27659749 0.80 MEN1 (0.43)
SCHEMBL7872934 0.79
SCHEMBL15090435 0.78 PSMB5 (0.31)
SCHEMBL6841493 0.77 GLRA1 (0.30) GLRA1SLC6A9OR51E2
SCHEMBL21955799 0.77 GLRA1 (0.39) ADRA1AGLRA1SLC6A9OR51E2
SCHEMBL8347563 0.74 PTGS1 (0.35)
SCHEMBL27606643 0.73 MEN1 (0.31)
SCHEMBL15136399 0.73 MVD (0.39) ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102358752-B GLP-1 and exendin related invention PHILIPPS UNIVERSITY MARBURG 2014-07-30 CN claimed
CN-102358752-A GLP-1 and exendin related invention PHILIPPS UNIVERSITY MARBURG 2012-02-22 CN claimed
CN-102304179-A With GLP-1 and the relevant invention of incretin analogue (exendin) UNIV MARBURG PHILIPPS 2012-01-04 CN claimed
CN-101010340-A Invention relating to GLP-1 and incretin analogue (exendin) UNIV MARBURG PHILIPPS (DE) 2007-08-01 CN claimed
EP-2311452-B2 Topical composition comprising n-acetyl glucosamine YU RUEY J (US) 2020-12-30 EP disclosed
EP-2311452-B9 Topical composition comprising n-acetyl glucosamine YU RUEY J (US) 2014-12-24 EP disclosed
CN-102358752-B GLP-1 and exendin related invention PHILIPPS UNIVERSITY MARBURG 2014-07-30 CN disclosed
US-RE44302-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-06-18 US disclosed
US-RE44017-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-02-19 US disclosed
CN-101010340-B Invention relating to GLP-1 and incretin analogue (exendin) UNIV MARBURG PHILIPPS 2012-11-28 CN disclosed
CN-102358752-A GLP-1 and exendin related invention PHILIPPS UNIVERSITY MARBURG 2012-02-22 CN disclosed
CN-102304179-A With GLP-1 and the relevant invention of incretin analogue (exendin) UNIV MARBURG PHILIPPS 2012-01-04 CN disclosed
CN-101010340-A Invention relating to GLP-1 and incretin analogue (exendin) UNIV MARBURG PHILIPPS (DE) 2007-08-01 CN disclosed
EP-1639994-A2 Topical composition comprising N-acetylaldosamines or N-acetylamino acids Yu, Ruey J., Dr. (US) 2006-03-29 EP disclosed
EP-1570840-A2 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2005-09-07 EP disclosed
US-6524593-B1 Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails TRISTRATA, INC. 2003-02-25 US disclosed
CN-1361766-A Tricyclic compounds having acyloxymethoxycarbonyl side chain SHIONOGI PHARMACEUTICAL & CO L (JP) 2002-07-31 CN disclosed
EP-1143925-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2001-10-17 EP disclosed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US disclosed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 WO disclosed