⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633350 | 0.88 | GLRA1 (0.32) | — | |
| SCHEMBL2819946 | 0.87 | TERT (0.31) | — | |
| SCHEMBL1493219 | 0.80 | GLRA1 (0.38) | — | |
| SCHEMBL468872 | 0.79 | PAOX (0.32) | — | |
| SCHEMBL15090435 | 0.78 | PSMB5 (0.31) | — | |
| SCHEMBL98566 | 0.78 | GLRA1 (0.47) | — | |
| SCHEMBL6841493 | 0.75 | GLRA1 (0.30) | — | |
| SCHEMBL27659749 | 0.74 | MEN1 (0.43) | — | |
| SCHEMBL27606643 | 0.74 | MEN1 (0.31) | — | |
| Glycine SCHEMBL4264488 | 0.74 | GLRA1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722291-A1 | COMPOSITIONS AND METHODS FOR MAGNETIC RESONANCE IMAGING, X-RAY IMAGING AND RADIOPHARMACEUTICALS | MALLINCKRODT MEDICAL, INC. (US) | 1996-07-24 | — | — | EP | claimed |
| WO-1995009564-A1 | COMPOSITIONS AND METHODS FOR MAGNETIC RESONANCE IMAGING, X-RAY IMAGING AND RADIOPHARMACEUTICALS | MALLINCKRODT MEDICAL, INC. (US) | 1995-04-13 | — | — | WO | claimed |
| CN-114377143-A | Compositions, methods and kits for diagnosing and treating disorders associated with CD206 expressing cells | 康德乐健康414有限责任公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-111447955-A | Use of 99 mTc-temarosaints and related molecular constructs for identifying and diagnosing malignancies and for monitoring therapeutic anti-tumor interventions | 纳维迪亚生物制药有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-110997014-A | CD206+ macrophage-specific molecular imaging probe compositions and methods and non-invasive quantification of macrophage infiltration from human arterial walls | 纳维迪亚生物制药有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-107106709-A | Radiopharmaceutical conjugates comprising a metabolite and an EPR agent targeting tumor cells | 南非核能源有限公司 | 2017-08-29 | — | — | CN | disclosed |
| US-6306073-B1 | Apparatus and method for treating a disease process in a luminal structure with a radionuclide and chelating agent | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2001-10-23 | — | — | US | disclosed |
| EP-0963182-A4 | METHOD OF TREATING A DISEASE PROCESS IN A LUMINAL STRUCTURE | UNIV COLUMBIA (US) | 2000-10-18 | — | — | EP | disclosed |
| EP-0963182-A1 | METHOD OF TREATING A DISEASE PROCESS IN A LUMINAL STRUCTURE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1999-12-15 | — | — | EP | disclosed |
| US-5924973-A | COMPLEX OF RADIONUCLIDE AND A CHELATING AGENT | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1999-07-20 | — | — | US | disclosed |
| WO-1998012979-A1 | METHOD OF TREATING A DISEASE PROCESS IN A LUMINAL STRUCTURE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-04-02 | — | — | WO | disclosed |
| EP-0722291-A1 | COMPOSITIONS AND METHODS FOR MAGNETIC RESONANCE IMAGING, X-RAY IMAGING AND RADIOPHARMACEUTICALS | MALLINCKRODT MEDICAL, INC. (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009564-A1 | COMPOSITIONS AND METHODS FOR MAGNETIC RESONANCE IMAGING, X-RAY IMAGING AND RADIOPHARMACEUTICALS | MALLINCKRODT MEDICAL, INC. (US) | 1995-04-13 | — | — | WO | disclosed |