Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468422 | 0.89 | DHODH (1.00) | DHODH | |
| SCHEMBL3667236 | 0.87 | DHODH (0.85) | DHODH | |
| SCHEMBL468503 | 0.83 | DHODH (0.78) | DHODH | |
| SCHEMBL15789871 | 0.82 | DHODH (0.71) | DHODH | |
| SCHEMBL15401638 | 0.82 | DHODH (0.80) | DHODH | |
| SCHEMBL15401201 | 0.80 | DHODH (0.62) | DHODH | |
| SCHEMBL468446 | 0.77 | DHODH (1.00) | DHODH | |
| SCHEMBL15401186 | 0.76 | DHODH (0.78) | DHODH | |
| SCHEMBL3664567 | 0.76 | DHODH (0.84) | DHODH | |
| SCHEMBL468722 | 0.74 | DHODH (1.00) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389197-A1 | COMBINATIONS COMPRISING METHOTREXATE AND DHODH INHIBITORS | Almirall S.A. (ES) | 2011-11-30 | — | — | EP | claimed |
| US-20110253957-A1 | Compliant motion distribution system | FLEXSYS, INC. | 2011-10-20 | — | — | US | claimed |
| WO-2010083975-A1 | COMBINATIONS COMPRISING METHOTREXATE AND DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2010-07-29 | — | — | WO | claimed |