Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.68 |
| ▸ | CTSL | P07711 | 18/20 | 0.68 |
| ▸ | CTSS | P25774 | 14/20 | 0.68 |
| ▸ | CTSB | P07858 | 6/20 | 0.68 |
| ▸ | CTSV | O60911 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4767207 | 0.90 | CTSK (0.84) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4686493 | 0.86 | CTSK (0.50) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4685643 | 0.81 | CTSK (0.68) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7435727 | 0.81 | CTSK (0.77) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4041991 | 0.81 | CTSK (0.46) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL12270440 | 0.81 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL8246857 | 0.81 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL30552817 | 0.81 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL15281233 | 0.81 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14131370 | 0.81 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1384713-B1 | 4-amino-azepan-3-one derivatives as protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 2008-10-15 | — | — | EP | claimed |