Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40295 | 0.92 | LRRK2 (0.49) | LRRK2F10RXFP1MAPTNPC1 | |
| SCHEMBL40848 | 0.89 | F10 (0.50) | LRRK2F10RXFP1MAPTNPC1 | |
| SCHEMBL1696944 | 0.86 | LRRK2 (0.47) | LRRK2F10RXFP1MAPTNPC1 | |
| SCHEMBL46917 | 0.86 | LRRK2 (0.48) | LRRK2F10RXFP1MAPTNPC1 | |
| SCHEMBL40465 | 0.85 | RXFP1 (0.52) | LRRK2F10RXFP1MAPTNPC1 | |
| SCHEMBL45586 | 0.84 | LRRK2 (0.46) | LRRK2F10RXFP1MAPTNPC1 | |
| SCHEMBL15444419 | 0.80 | LRRK2 (0.42) | LRRK2F10RXFP1MAPTNPC1 | |
| SCHEMBL46907 | 0.80 | F10 (0.51) | LRRK2F10MAPTNPC1RAB9A | |
| SCHEMBL10148534 | 0.79 | LCK (0.42) | LRRK2F10RXFP1KMT2AMEN1 | |
| SCHEMBL15433035 | 0.78 | DGAT1 (0.45) | LRRK2F10RXFP1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |