Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689746 | 0.79 | CCR5 (0.77) | CCR5 | |
| SCHEMBL4693380 | 0.77 | CCR5 (0.49) | CCR5 | |
| SCHEMBL4697296 | 0.74 | CCR5 (0.72) | CCR5 | |
| SCHEMBL4693263 | 0.73 | CCR5 (0.75) | CCR5 | |
| SCHEMBL13359865 | 0.72 | TDP1 (0.62) | CCR5 | |
| SCHEMBL4694312 | 0.72 | CCR5 (0.69) | CCR5 | |
| SCHEMBL5231134 | 0.72 | CCR5 (0.73) | CCR5 | |
| SCHEMBL4695094 | 0.72 | CCR5 (0.71) | CCR5 | |
| SCHEMBL5313742 | 0.71 | CCR5 (0.78) | CCR5 | |
| SCHEMBL13326722 | 0.70 | CCR5 (0.52) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |