Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 3/20 | 0.42 |
| ▸ | FLT4 | P35916 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683789 | 0.97 | MEN1 (0.44) | CCR3PDE4DFLT1FLT4KDR | |
| SCHEMBL4688854 | 0.92 | CCR3 (0.45) | CCR3FLT1KDRMCHR1MEN1 | |
| SCHEMBL4240643 | 0.90 | PDE4D (0.42) | PDE4DFLT1FLT4KDRHTR4 | |
| SCHEMBL4688007 | 0.90 | CCR3 (0.44) | CCR3FLT1KDRMCHR1MEN1 | |
| SCHEMBL4540719 | 0.89 | MCHR1 (0.44) | CCR3HTR4MCHR2MCHR1POLB | |
| SCHEMBL4688728 | 0.89 | MCHR1 (0.47) | CCR3KDRHTR4MCHR2MCHR1 | |
| SCHEMBL4684563 | 0.88 | KDR (0.44) | CCR3PDE4DFLT1KDRMCHR1 | |
| SCHEMBL4240272 | 0.87 | LMNA (0.42) | PDE4DFLT1FLT4KDRHTR4 | |
| SCHEMBL4689230 | 0.86 | CCR3 (0.42) | CCR3FLT1KDRHTR4MCHR1 | |
| SCHEMBL4686866 | 0.85 | CCR3 (0.44) | CCR3FLT1KDRMCHR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |