Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.72 |
| ▸ | IKBKB | O14920 | 8/20 | 0.51 |
| ▸ | FYN | P06241 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19466738 | 0.88 | MKNK1 (0.66) | MKNK1IKBKBFYN | |
| SCHEMBL16331673 | 0.84 | MKNK1 (0.72) | MKNK1FYN | |
| SCHEMBL2948860 | 0.81 | FYN (0.71) | MKNK1IKBKBFYN | |
| SCHEMBL19466740 | 0.79 | MKNK1 (0.64) | MKNK1FYN | |
| SCHEMBL2948850 | 0.78 | MKNK1 (0.67) | MKNK1IKBKBFYN | |
| SCHEMBL3036460 | 0.78 | FYN (0.76) | MKNK1IKBKBFYN | |
| SCHEMBL2947844 | 0.78 | IKBKB (0.58) | MKNK1IKBKBFYN | |
| SCHEMBL2951003 | 0.77 | FYN (0.71) | MKNK1FYN | |
| SCHEMBL4691104 | 0.77 | FYN (0.74) | MKNK1IKBKBFYN | |
| SCHEMBL3453200 | 0.76 | MKNK1 (0.56) | MKNK1IKBKBFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | claimed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | claimed |
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |