Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.60 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695353 | 0.87 | CNR1 (0.45) | CNR1 | |
| SCHEMBL4690363 | 0.75 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL14545377 | 0.71 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL5804650 | 0.68 | CNR1 (0.46) | CNR1CRHR1CNR2 | |
| SCHEMBL4748379 | 0.67 | CNR1 (0.61) | CNR1CNR2KCNH2 | |
| SCHEMBL14523353 | 0.67 | CNR1 (0.73) | CNR1CNR2KCNH2 | |
| SCHEMBL4748006 | 0.67 | CNR1 (0.61) | CNR1CNR2KCNH2 | |
| SCHEMBL4748627 | 0.66 | CNR1 (0.72) | CNR1CNR2KCNH2 | |
| SCHEMBL4691515 | 0.66 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4453192 | 0.66 | CNR1 (0.64) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871762-A2 | SUBTITUTED HETEROARYL CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006113704-A2 | SUBTITUTED HETEROARYL CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |