Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.61 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14523353 | 0.92 | CNR1 (0.73) | CNR1CNR2KCNH2 | |
| SCHEMBL4748006 | 0.89 | CNR1 (0.61) | CNR1CNR2KCNH2 | |
| SCHEMBL4748627 | 0.81 | CNR1 (0.72) | CNR1CNR2KCNH2 | |
| SCHEMBL4690363 | 0.76 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4691382 | 0.74 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL14545377 | 0.72 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4691515 | 0.67 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4690364 | 0.67 | CNR1 (0.60) | CNR1CNR2KCNH2 | |
| SCHEMBL14545361 | 0.67 | CNR1 (0.91) | CNR1CNR2 | |
| SCHEMBL4695662 | 0.67 | CNR1 (0.48) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871762-A2 | SUBTITUTED HETEROARYL CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006113704-A2 | SUBTITUTED HETEROARYL CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |