Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345828 | 0.77 | KCNN4 (0.58) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 | |
| SCHEMBL1829408 | 0.77 | TSHR (0.58) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 | |
| SCHEMBL3868401 | 0.77 | KCNN4 (0.58) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 | |
| SCHEMBL7144750 | 0.77 | KCNN4 (0.58) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 | |
| SCHEMBL1436199 | 0.77 | KCNN4 (0.58) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 | |
| SCHEMBL10954237 | 0.77 | TSHR (0.58) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL9576091 | 0.74 | KCNN4 (0.55) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 | |
| SCHEMBL4177593 | 0.72 | KCNN4 (0.52) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 | |
| SCHEMBL5184997 | 0.72 | KCNN4 (0.52) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 | |
| SCHEMBL6930353 | 0.72 | KCNN4 (0.52) | KCNN4TSHRCYP1A2ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100513397-C | Pyridine n-oxide compounds as phosphodiesterase 4 inhibitors | MEMORY PHARM CORP (US) | 2009-07-15 | — | — | CN | claimed |
| CN-1714081-A | Phosphodiesterase 4 inhibitors | MEMORY PHARM CORP (US) | 2005-12-28 | — | — | CN | claimed |
| CN-101730680-A | Has 5-HT 64 ' the compound that replaces of receptor affinity | MEMORY PHARM CORP | 2010-06-09 | — | — | CN | disclosed |
| CN-101641329-A | Has 5-HT 6Indoles and indazole derivatives that 6 ＇ of receptor affinity replace | MEMORY PHARM CORP US | 2010-02-03 | — | — | CN | disclosed |
| CN-100513397-C | Pyridine n-oxide compounds as phosphodiesterase 4 inhibitors | MEMORY PHARM CORP (US) | 2009-07-15 | — | — | CN | disclosed |
| EP-1984351-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | Memory Pharmaceuticals Corporation (US) | 2008-10-29 | — | — | EP | disclosed |
| CN-100378075-C | Aniline derivatives useful as phosphodiesterase 4 inhibitors | MEMORY PHARMACEUTICALS INC (US) | 2008-04-02 | — | — | CN | disclosed |
| WO-2007098418-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-08-30 | — | — | WO | disclosed |
| CN-1922144-A | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs | MEMORY PHARM CORP (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1714081-A | Phosphodiesterase 4 inhibitors | MEMORY PHARM CORP (US) | 2005-12-28 | — | — | CN | disclosed |
| CN-1688545-A | phosphodiesterase 4 inhibitors, including N-substituted aniline and diphenylamine analogs | MEMORY PHARM CORP (US) | 2005-10-26 | — | — | CN | disclosed |
| CN-1498211-A | Aniline derivative using as phosphodiesterase 4 inhibitor | ����˹��ҩ�﹫˾ | 2004-05-19 | — | — | CN | disclosed |