SCHEMBL4690566

SCHEMBL4690566

Cc1cc(NC(=O)Oc2ccc3[nH]c(-c4ccc(Cl)s4)nc3c2)ccc1N1CCOCC1=O

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3864913 0.90 F10 (0.90) F10
SCHEMBL4694064 0.89 F10 (0.70) F10
SCHEMBL3864246 0.88 F10 (0.71) F10
SCHEMBL3866754 0.86 F10 (0.89) F10
SCHEMBL28755710 0.85 F10 (0.68) F10
SCHEMBL3868923 0.84 F10 (0.90) F10
SCHEMBL3871839 0.83 F10 (0.71) F10
SCHEMBL6508642 0.79 F10 (0.60) F10
SCHEMBL3861752 0.79 F10 (0.58) F10
SCHEMBL3862829 0.78 F10 (0.89) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558247-B1 BENZIMIDAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2008-02-20 EP claimed
EP-1558247-B1 BENZIMIDAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2008-02-20 EP disclosed