SCHEMBL4694064

SCHEMBL4694064

O=C(Nc1ccc(N2CCOCC2=O)cc1)Oc1ccc2[nH]c(-c3ccc(Cl)s3)nc2c1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4690566 0.89 F10 (0.72) F10
SCHEMBL3862829 0.89 F10 (0.89) F10
SCHEMBL3864159 0.87 F10 (0.88) F10
SCHEMBL3868420 0.85 F10 (0.65) F10
SCHEMBL3864251 0.85 F10 (0.88) F10
SCHEMBL3868472 0.85 F10 (0.73) F10
SCHEMBL3862475 0.83 F10 (0.89) F10
SCHEMBL3866094 0.83 F10 (0.88) F10
SCHEMBL3862576 0.82 F10 (0.70) F10
SCHEMBL3864899 0.80 F10 (0.63) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558247-B1 BENZIMIDAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2008-02-20 EP claimed
EP-1558247-B1 BENZIMIDAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2008-02-20 EP disclosed