Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690578 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL4740656 | 0.88 | KMT2A (0.50) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL4740658 | 0.88 | KMT2A (0.50) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL4229236 | 0.86 | KMT2A (0.44) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL4684023 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL4684021 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL4231989 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL4683454 | 0.80 | MEN1 (0.62) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL4687842 | 0.78 | KMT2A (0.54) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL4687845 | 0.78 | KMT2A (0.54) | MEN1KMT2AMAPTMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |