Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966241 | 0.84 | CRHR1 (0.44) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3967630 | 0.84 | CRHR1 (0.44) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3966232 | 0.84 | CRHR1 (0.44) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3965211 | 0.83 | CRHR1 (0.47) | CRHR1CRHR2SMPD3 | |
| SCHEMBL4689714 | 0.82 | CRHR1 (0.47) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3965276 | 0.82 | CRHR1 (0.46) | CRHR1CRHR2 | |
| SCHEMBL3962421 | 0.82 | CRHR1 (0.46) | CRHR1CRHR2 | |
| SCHEMBL3965873 | 0.82 | CRHR1 (0.46) | CRHR1CRHR2 | |
| SCHEMBL3966304 | 0.82 | CRHR1 (0.40) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3962691 | 0.82 | CRHR1 (0.43) | CRHR1CRHR2SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879896-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006107784-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |