Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | PTGFR | P43088 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696672 | 0.92 | PTGER4 (0.35) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL14573777 | 0.90 | IDH1 (0.34) | PTGER4 | |
| SCHEMBL14573778 | 0.89 | IDH1 (0.34) | PTGER4 | |
| SCHEMBL12378082 | 0.88 | IDH1 (0.34) | PTGER4 | |
| SCHEMBL12378107 | 0.88 | KEAP1 (0.34) | PTGER4PTGDR | |
| SCHEMBL4691020 | 0.87 | PTGER4 (0.35) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL12378101 | 0.87 | IDH1 (0.33) | PTGER4 | |
| SCHEMBL14573781 | 0.87 | PTGER4 (0.33) | PTGER4 | |
| SCHEMBL5645681 | 0.87 | IDH1 (0.34) | PTGER4 | |
| SCHEMBL12378113 | 0.86 | TP53 (0.35) | PTGER4PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888581-A2 | HIV-INTEGRASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125048-A2 | HIV-INTEGRASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-11-23 | — | — | WO | disclosed |