Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471985 | 0.91 | CNR2 (0.51) | FAAHROCK1CA1CA2CA4 | |
| SCHEMBL13708832 | 0.91 | CNR2 (0.51) | FAAHROCK1CA1CA2CA4 | |
| SCHEMBL4466286 | 0.81 | ROCK1 (0.54) | FAAHROCK1CA1CA2CA4 | |
| SCHEMBL4466288 | 0.81 | ROCK1 (0.54) | FAAHROCK1CA1CA2CA4 | |
| SCHEMBL4469872 | 0.81 | ROCK1 (0.54) | FAAHROCK1CA1CA2CA4 | |
| SCHEMBL4476870 | 0.81 | CNR2 (0.52) | ROCK1CA1CA2CA4CA9 | |
| SCHEMBL4475802 | 0.79 | CNR2 (0.51) | FAAHROCK1CA1CA2CA4 | |
| SCHEMBL4471991 | 0.77 | CNR2 (0.54) | ROCK1CA1CA2CA4CA9 | |
| SCHEMBL4481105 | 0.77 | CNR2 (0.54) | ROCK1CA1CA2CA4CA9 | |
| SCHEMBL4471986 | 0.77 | CNR2 (0.54) | ROCK1CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |